Microcrystalline cellulose (MCC) powder was prepared by acid treatment of the cellulose extracted from oil palm empty fruit bunch (EFB) fibre (Ramli et al., 2015, Rosnah et al., 2009). Traditionally MCC was obtained from wood, cotton (Suzuki and Nakagami, 1999), and cotton linters (Nada et al., 2009). There are a few reports of MCC derived from agriculture biomass such as rice straw and bagasse (Ilindra and Dhake, 2008), sawdust (Oyeniyi and Itiola, 2012), kenaf core wood (Chi et al., 2013), Lageriana siceraria (water gourd) (Achor et al., 2014), soyabean hulls (Merci et al., 2015), oil palm fronds (Hussin, et al., 2016) and oil palm trunks (Abd Hamid et al., 2014).